Central Michigan University

Ceftaroline Diffusion Into Cerebrospinal Fluid of Children With Ventriculitis Due to Ventriculoperitoneal Shunt Infection

BACKGROUND: Data on ceftaroline cerebrospinal fluid (CSF) levels in children are limited. This study examined ceftaroline diffusion into CSF among children with ventriculoperitoneal shunt (VPS)-related ventriculitis and external ventricular drains. METHODS: Patients received a si...

Safety of Subcutaneous Heparin in Patients Requiring External Ventricular Drains.

BACKGROUND AND OBJECTIVES: External ventricular drain (EVD) placement and removal to manage intracranial pressure carry an inherent risk of hemorrhage, which complicates chemoprophylactic management of venous thromboembolism (VTE). VTE chemoprophylaxis with subcutaneous (SQ) hepa...

Accidental Toxicological Pediatric Ingestions: Disparities in the Involvement of Social Work and Child Protective Services

OBJECTIVES: To examine sociodemographic and clinical factors associated with social work consultation and child protective services (CPS) referrals among children presenting to the pediatric emergency department (ED) after an accidental toxicological ingestion. METHODS: This retr...

“You have no grit:” A qualitative exploration of barriers to eating disorder care in the rural United States

This qualitative study explored the barriers to eating disorder (ED) treatment among adults with EDs in a rural state. Study participants were adults with a confirmed ED who lived in a rural region of one rural state in the United States. Braun & Clarke’s (2006) thematic analysis...

Multi-year, winter-specific wastewater surveillance during and after the COVID-19 pandemic reveals temporal changes in antibiotic resistance genes, mobile genetic elements, and bacterial communities

Evidence suggests that antimicrobial resistant organisms were able to proliferate during and after the COVID-19 pandemic due to antibiotic misuse, attempts to find appropriate COVID-19 treatment, and secondary infection treatment. Wastewater surveillance has allowed for community...

Knotworking With Artificial Intelligence: A Case Study of Emergent Student User-Experience Composition With AI-Assisted Cocreation

This case study examines how technical communication students used generative artificial intelligence (GenAI) in user-experience (UX) design via Figma. Over a semester, they engaged with Figma Jambot, AI plug-ins, and other GenAI tools. Reporting on the findings from students’ in...

Spokane regional health district workplace mental health and well-being assessment

Public health agencies protect and promote population health under conditions of chronic underfunding, political scrutiny, and high demand, creating a distinct set of stressors for their workforce; yet the mental health and well-being of the local governmental public health workf...

Flexible Supervision Model for Clinical Education in a Doctor of Audiology Program

Purpose: Effective clinical supervision is essential to audiology education, ensuring student development and high-quality patient care. This report describes the implementation of a flexible supervision model in a doctor of audiology program at Purdue University. Method: The mod...

How Social Networks Help with Proactive Resilience: Evidence from Chinese Companies

This study examines how social networks enable emerging market firms to develop, strengthen, and sustain proactive resilience in a turbulent global environment. Drawing on interviews with top managers in selected Chinese multinational firms, the study identifies three network pil...

Growth during the first year of life following prenatal opioid exposure: A retrospective cohort study

Objectives: Opioid use during pregnancy is common and has been shown to affect fetal growth, increasing from 6.5 to 23 per 1,000 live births over the past decade. Prenatal exposure to opioids can result in neonatal opioid withdrawal syndrome (NOWS) and is associated with a higher...

EEG vs. Hybrid EEG–fNIRS BCI for FES Control in Healthy Subjects: A Blind Randomized Study and an Open Dataset

Among the various brain–computer interface (BCI) modifications used in post-stroke rehabilitation, BCI systems combined with functional electrical stimulation (FES) are considered the most effective. As a preliminary step toward optimizing such systems for clinical application, i...

Stricter Regulation in the United States of Direct-to-Consumer Drug Advertising: Better, but Not Enough.

. 2026;116(9): 1352-1357. https://doi.org/10.2105/AJPH.2026.308469).

Photobiomodulation therapy and polyethylene glycol as monotherapy versus combination treatment in male and female rats following spinal cord injury

Abstract Purpose Spinal cord injury (SCI) is a neurological disorder that causes motor and sensory dysfunction. Recent studies suggest that combination therapies are promising, as they target multiple mechanisms. Photobiomodulation therapy (PBMT) has been shown to reduce inflamma...

Disparity in Clinical Presentation and Utilization of Atherectomy for Peripheral Arterial Disease: An Analysis of the OEIS National Registry

BACKGROUND: Racial and socioeconomic disparities exist in patients with peripheral arterial disease (PAD) and their treatment. We examined factors that may affect utilization of atherectomy in an office-based setting using a national outpatient registry. METHODS: Data were analyz...

Cord Blood DNA Methylation and Large-for-Gestational-Age Birth: A Pilot Epigenome-Wide Study in the GROW Cohort

Background/Objectives: Large-for-gestational-age (LGA) birth is associated with adverse perinatal outcomes and increased risk of metabolic disease later in life. Despite these risks, epigenetic studies of LGA remain limited, particularly those using umbilical cord blood DNA methy...