Central Hospital of Putuo District

Sequential method for determining the effective dose of remimazolam combined with sufentanil for cervical dilation in hysteroscopic surgery

This study investigated the 50% and 95% effective doses (ED50 and ED95) of remimazolam combined with sufentanil for cervical dilation during hysteroscopic surgery. Prospective single-center dose-finding study using a modified Dixon up-and-down sequential method. Twenty-five patie...

Colorectal cancer-derived IGFBP2 promotes liver metastasis by driving intrahepatic fibrotic pre-metastatic niche formation

Colorectal cancer (CRC) liver metastasis (LM) is a leading cause of cancer-related death, with pre-metastatic niche (PMN) formation being critical for metastasis. Insulin-like growth factor binding protein 2 (IGFBP2) is overexpressed in metastatic CRC, but its role in intrahepati...

Dental caries among 12-year-old adolescents in shanghai: a cross-sectional study on prevalence, severity, and associated risk factors

This study aimed to assess the prevalence, severity, and associated factors of dental caries in permanent teeth among 12-year-old adolescents in Shanghai, China. A cross-sectional study was conducted in 2021 among 1,305 adolescents from six randomly selected districts. Clinical e...

Association between the time window of rash recurrence and the risk of renal involvement within 6 months in children with immunoglobulin A vasculitis

Renal involvement is a major determinant of long-term outcome in childhood immunoglobulin A vasculitis (IgAV). We examined whether the timing of the initial rash recurrence was associated with renal involvement within 180 days, while accounting for temporal ordering, rash phenoty...