Central Hospital Affiliated to Shenyang Medical College

Digital health interventions across the cancer control continuum: an umbrella review of systematic reviews and meta-analyses of randomised controlled trials

Given the rising global cancer burden and fragmented evidence on digital health interventions (DHIs), this umbrella review synthesizes evidence on DHIs across the cancer control continuum to inform evidence-based practice. We systematically searched PubMed, Medline (via Ovid), We...

Combined metabolomics and microbiota analysis reveals the therapeutic effect of indole-3-propionic acid on ovariectomy-induced osteoporosis

<title>Abstract</title> Background Osteoporosis is a process of bone tissue destruction jointly caused by chronic inflammation and oxidative stress. Indole-3-propionic acid (IPA), as a metabolic molecule of the gut microbiota, exerts anti-inflammatory and antioxidant properties....

The Landscape of Biomarkers in ICU ‐Associated AKI : From Protein Markers to Cell‐Free Nucleic Acids

BACKGROUND: Acute kidney injury (AKI) affects approximately 30%-60% of intensive care unit (ICU) admissions, but early detection remains difficult because creatinine- and urine-output-based KDIGO criteria are delayed and confounded in critical illness. OBJECTIVE: To summarize the...