Central Hospital Affiliated to Shenyang Medical College

Combined metabolomics and microbiota analysis reveals the therapeutic effect of indole-3-propionic acid on ovariectomy-induced osteoporosis

<title>Abstract</title> Background Osteoporosis is a process of bone tissue destruction jointly caused by chronic inflammation and oxidative stress. Indole-3-propionic acid (IPA), as a metabolic molecule of the gut microbiota, exerts anti-inflammatory and antioxidant properties....

The Landscape of Biomarkers in ICU ‐Associated AKI : From Protein Markers to Cell‐Free Nucleic Acids

BACKGROUND: Acute kidney injury (AKI) affects approximately 30%-60% of intensive care unit (ICU) admissions, but early detection remains difficult because creatinine- and urine-output-based KDIGO criteria are delayed and confounded in critical illness. OBJECTIVE: To summarize the...