Center for Rheumatology

The impact of non-medical determinants of health on patient-reported outcomes in pediatric lupus: A CARRA registry study

Objectives Social determinants of health (SDOH) and race are associated with disease activity, including lower achievement of the low lupus disease activity state (LLDAS), but it is unknown whether these factors are associated with patient-reported outcomes (PROs). Among a cohort...

Unilateral Sacroiliac Hemiagenesis in a Young Woman Presenting With Chronic Mechanical Low Back and Buttock Pain: A Case Report

Sacral agenesis is a rare congenital malformation belonging to the spectrum of caudal regression syndrome, whose clinical manifestations are highly variable and depend on the phenotype of the disease.We report the case of a young woman who presented with chronic mechanical low ba...

A comparative study of gait parameters and body composition in athletes and sedentary individuals

This cross-sectional investigation was undertaken to explore and compare the potential distinctions in segmental body composition and gait characteristics-encompassing plantar pressure distribution and spatiotemporal parameters-between young male athletes engaged in dynamic, high...

Novel therapies for refractory idiopathic inflammatory myopathy-associated interstitial lung disease

PURPOSE OF REVIEW: Idiopathic inflammatory myopathies (IIM) are systemic autoimmune rheumatic diseases in which interstitial lung disease (ILD) is a frequent extra-muscular manifestation and a major driver of morbidity and mortality. ILD occurs most commonly in antisynthetase syn...

Effects of exercise on muscle strength and characteristics in rheumatic diseases and sarcopenia: Protocol for the Care for Muscle (C4M) Study

Objective Muscle weakness is prevalent in rheumatoid arthritis (RA), osteoarthritis (OA) and sarcopenia (SARC). Endurance exercises may improve mitochondrial function and oxidative capacity, while strength exercises are thought to stimulate myofibrillar protein synthesis. This st...

Expanding the Role of Dalbavancin in Children: A Case Series and Systematic Review

BACKGROUND: Dalbavancin is a long-acting lipoglycopeptide antibiotic with activity against Gram-positive bacteria and is approved for the treatment of acute bacterial skin and skin structure infections. Its pharmacokinetic profile and tolerability make it an attractive option for...