Centenary Institute

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

ABSTRACT Ductal carcinoma in situ (DCIS) is a non‐invasive precursor of invasive ductal carcinoma (IDC), yet the biological mechanisms underlying the transition from DCIS to IDC remain incompletely understood. Here, we integrate spatial transcriptomics, single‐cell RNA sequencing...

Unmasking the Influence of Viral Micro‐RNAs on Host Immunity

ABSTRACT Micro‐RNAs (miRNAs) are key regulators of human immunity, controlling critical cellular programmes including proliferation, differentiation, apoptosis, and immune activation to shape the host response to infection. Multiple human‐infecting viruses encode their own miRNA...