Centar za Promociju Nauke

Association of FOXP3 Gene Polymorphisms with Skin, Vulvar and Ectocervical Squamous Cell Tumors

Background and Objectives: Squamous cell tumors arise from squamous epithelial cells. Polymorphisms in the FOXP3 gene may influence malignancy susceptibility. This study evaluated the potential association of FOXP3 rs3761548 (−3279 A/C) and rs2280883 (IVS9+459 T/C) polymorphisms...

Williams–Campbell syndrome in an adult previously treated as allergic bronchopulmonary aspergillosis: a diagnostic challenge

Abstract Introduction Williams-Campbell Syndrome (WCS) is a rare congenital syndrome of unknown origin, characterized by defective or completely absent bronchial wall cartilage which can lead to distal airway collapse, forming bronchiectasis distal to the collapsed bronchi. The e...

Targeting MicroRNA-21 in Chronic Kidney Disease: Lessons from the Lademirsen Story

MicroRNA-21 (miR-21) has long been regarded as one of the most promising molecular targets in chronic kidney disease (CKD) because of its consistent upregulation across diverse renal disorders and its involvement in fibrosis, inflammation, oxidative stress, and metabolic dysfunct...

Integrated Bioinformatic and Experimental Analysis of SLFN11 Expression and Clinical Significance in Locally Advanced Rectal Cancer

Background/Objectives: Schlafen 11 (SLFN11) encodes a DNA damage response protein implicated in sensitivity to DNA-damaging therapies and has been proposed as a predictive biomarker in several malignancies. This study aimed to characterize SLFN11 expression and evaluate its progn...

Integrated Chemical, Computational, and Cellular Profiling of a Dual-Oil Melanoma Formulation: An Exploratory Life-Science Study

Background: Previous studies have examined bioactive constituents of Prunus dulcis oil, Pinus sylvestris essential oil, and related phytochemical matrices separately; however, their combined chemical profile, comparator-context molecular-docking landscape, and comparative cellula...

Perioperative tranexamic acid and postoperative haematuria after transvesical prostatectomy: a prospective observational cohort study

Bleeding and postoperative haematuria remain clinically relevant after open simple prostatectomy. Tranexamic acid (TXA) may reduce bleeding through antifibrinolytic activity, but evidence in open prostate surgery for benign prostatic obstruction is limited. This study evaluated p...