Catholic Medical Center

Predicting clinical dementia rating scores from neuropsychological testing: a machine learning study in a large clinical cohort

To reduce variability of Clinical Dementia Rating (CDR) assessments taken from raters and informants, quantitative and reproducible approaches to support consistent interpretation are needed. We developed multiclass classification models of CDR global and regression models of CDR...

When the yardstick is the variable: the fractional flow reserve threshold as a reference standard in second-line functional imaging

António Miguel Ferreira, MD, Luís Raposo, MD, PhD, Sérgio Baptista, MD, PhD; When the yardstick is the variable: the fractional flow reserve threshold as a

Osimertinib-Associated Cardiotoxicity in EGFR-Mutant Non–Small Cell Lung Cancer: Mechanisms, Phenotypes, and Surveillance

Osimertinib, a third-generation EGFR-TKI, is now the standard first-line treatment for EGFR-mutant non–small cell lung cancer and is increasingly given in the adjuvant setting for up to 3 years and in combination with chemotherapy. As exposure has lengthened and shifted toward cu...