Carolinas Medical Center

Association of Irreversible Electroporation Treatment with Overall Survival in Stage III Pancreatic Ductal Adenocarcinoma: DIRECT Registry Results

Abstract Background Irreversible electroporation (IRE) is used in selected patients with Stage III pancreatic ductal adenocarcinoma (PDAC), but its association with survival relative to standard-of-care (SOC) therapy remains uncertain. Methods This multicenter observational study...

Hybrid/collision ameloblastoma-ameloblastic fibroma: a case with molecular features supporting a tumor-in-tumor model

Hybrid/collision odontogenic tumors are a rare and controversial phenomenon not formally recognized as a distinct category in the WHO Classification of Head and Neck Tumors and their diagnosis relies mainly on histomorphology. This report presents a unique mandibular odontogenic...

Prevalence and cardiac outcomes of T wave inversions in high school athletes: an analysis of 15 years of preparticipation screening ECGs

Objective To characterise the prevalence, distribution pattern and clinical relevance of T wave inversion (TWI) on a screening preparticipation 12-lead ECG in high school athletes. Methods A retrospective cohort study analysed ECGs from athletes screened between 2010 and 2025 dur...

Obstructive shock from delayed blunt cardiac injury after chest trauma

Blunt cardiac injury (BCI) is a rare but serious presentation in emergency departments (EDs) nationwide. These injuries arise in trauma and may be accompanied by confounding injuries that complicate the clinical picture. Timely recognition is crucial, as BCI may lead to complicat...