Carbon Engineering (Canada)

Autologous Hematopoietic Stem Cell Transplantation in Aquaporin-4 Immunoglobulin G–Positive Neuromyelitis Optica Spectrum Disorder After Satralizumab Failure

Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune astrocytopathy mediated by aquaporin-4 immunoglobulin G (AQP4-IgG), characterized by recurrent inflammatory events affecting predominantly the optic nerves and spinal cord. Despite the availability of targeted...