Canadian Institute for Advanced Research

A niche construction-based approach to evolution by natural selection without reproduction—proof of concept and implications

Abstract In past decades, conceptual analysis has established that evolution by natural selection (ENS) can occur without reproduction (Bouchard 2008 Philos. Sci. 75, 560–570 (doi:10.1086/594507); Papale, 2021 Synthese 198, 10 429–10 455 (doi:10.1007/s11229-020-02729-6)). The aim...

High-Field Specific Heat and Fundamental Superconducting Properties of the Single-Phase Type-II Superconductor V 3 Si

The specific heat data above the upper critical magnetic field H c2 , the angular dependence of H c2 , and fundamental superconducting parameters were consequently determined. The V 3 Si sample used in this research does not exhibit the structural transition and its high quality...

Measuring the contents of hallucinations from psychedelics and stroboscopic light: the Six-Dimensional Visual Hallucination Questionnaire

Abstract Hallucinations arise from disruptions in neural processes that construct perceptual experience from sensory input. Progress in consciousness science may therefore benefit from methods that precisely characterize their phenomenology. We provide an initial validation of th...

DyAb: sequence-based antibody design and property prediction in a low-data regime

ABSTRACT Protein therapeutic design and property prediction are frequently hampered by data scarcity. Here we propose a new model, DyAb, that addresses these issues by leveraging a pair-wise representation to predict differences in protein properties, rather than absolute values....

Longitudinal changes in gut microbiota across reproductive states in wild baboons

Background: In humans and other mammals, female reproduction is linked to extensive changes in physiology, immunity, hormones, and behavior. These changes likely shape, and may be shaped by, the composition of gut microbial communities. Characterizing the dynamics of gut microbia...