California Institute for Biomedical Research

An AI-Assisted Workflow for Rapid Prioritization of FDA-Approved Drugs as HDAC3 Inhibitor Candidates for Drug Repurposing

Epigenetic regulation through histone acetylation plays a critical role in gene expression and cancer progression. Because of its pivotal role in chromatin remodeling, Histone deacetylase 3 (HDAC3) has become a promising therapeutic target. In this study, an artificial intelligen...