Calgary Laboratory Services

Cognitive reserve and everyday functioning in cognitively unimpaired older adults: evidence from the CAN-PROTECT study

Abstract Background Cognitive reserve (CR) is thought to buffer against the clinical manifestation of dementia, preserving cognitive function despite accumulating pathology. However, less is known about how CR relates to the capacity to independently perform activities of daily l...

Placentitis and abortion caused by canine distemper virus in a Linnaeus’s two-toed sloth

Canine distemper virus (CDV; family Paramyxoviridae , taxon species Morbillivirus canis ) causes systemic disease in a broad range of mammalian hosts. CDV commonly targets epithelial, lymphoid, and nervous tissues. Reproductive disease is reported less frequently. Here, we descri...

Taming the Fire: Lung Sparing MDA-5 DM and MAS Overlap Successfully Treated with Methylprednisolone, Rituximab, IVIG, Anakinra, and Tofacitinib

Background Anti-melanoma differentiation-associated protein 5 (MDA5) Dermatomyositis (DM) can be refractory to multiple lines of immunosuppression.[1] Here, we present a case of refractory MDA-5 DM with Macrophage Activation Syndrome (MAS) overlap requiring numerous immunosuppres...