Bundeswehrzentralkrankenhaus Koblenz

Clindamycin under pressure: resistance in hospitalized patients with odontogenic infections and a penicillin allergy label – a multicenter retrospective study

Odontogenic infections may progress to deep space infection with systemic complications and require prompt surgical drainage and, when indicated, systemic antibiotics. In patients with a documented penicillin allergy label, empiric therapy is often shifted toward clindamycin, alt...

Effect of prehospital cervical spine immobilization on mortality and neurological outcome in trauma patients: an observational cohort study with propensity score matching based on the trauma registry of the German trauma society (TraumaRegister DGU®)

Abstract Background Prehospital cervical spine immobilization is standard trauma care intended to prevent secondary spinal cord injury, yet evidence for its effectiveness is limited, and adverse effects are increasingly recognized. Large registry-based comparisons accounting for...

Does age matter? acute appendicitis in octogenarians vs. younger patients - results of a German multicenter analysis

Abstract Background Acute appendicitis is a common indication for emergency abdominal surgery. Octogenarians (≥ 80 years) are considered high risk due to comorbidities and reduced physiological reserve. This study examined age-related differences in symptoms, surgical management,...

Clinical characteristics, treatment patterns, and survival outcomes in ductal prostate cancer: a multicenter retrospective analysis

Abstract Purpose Prostatic ductal adenocarcinoma (PDA) is a rare, aggressive prostate cancer subtype associated with advanced disease and poorer prognosis than acinar adenocarcinoma. Small ductal components influence management and preclude active surveillance. This study analyze...