Breast Cancer Now

Understanding experiences of recognising and reporting signs of recurrence following breast cancer: mapping behavioural determinants to optimise follow-up care

Abstract Purpose Approximately 20% of people affected by breast cancer experience recurrence. Shifts to personalised stratified follow-up (PSFU) in the United Kingdom and internationally require individuals to initiate further appointments themselves if they suspect recurrence. W...

Retrotransposable element derepression distinguishes DNMT3A-mutant from TET2-mutant clonal haematopoiesis

Clonal haematopoiesis (CH) is driven by somatic mutations in haematopoietic stem cells that generate clonal populations detectable in peripheral blood and is present in 10-20% of individuals over the age of 65. Mutations in DNMT3A and TET2 are the most common drivers and have bee...

Physical activity in advanced urological cancers undergoing immune checkpoint inhibitor treatment: a qualitative study exploring patient perspectives and experiences

Physical activity (PA) can improve health and treatment outcomes in cancer patients. However, patients with advanced cancer undergoing immune checkpoint inhibitor (ICI) therapy often experience debilitating side-effects that impact PA participation. Because PA experiences in pati...