Brain and Cognition Discovery Foundation

Association Between Dextromethorphan/Bupropion with Diabetes Mellitus and Hyperglycemia: Reports to the Food and Drug Administration Adverse Event Reporting System (FAERS)

IntroductionDextromethorphan/bupropion (DXM/BUP) is the first orally administered antidepressant approved by the United States Food and Drug Administration (U.S. FDA) that combines dextromethorphan (i.e., a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist and sigma...