B.P. Koirala Institute of Health Sciences

Proliferative glomerulonephritis with monoclonal IgM-kappa deposits responsive to daratumumab therapy—a case report

Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is a rare kidney disorder characterized by immune-complex-like glomerular deposits. Its pathogenesis remains unclear, is often linked to monoclonal gammopathy of renal significance (MGRS), but effec...

A cross-sectional study of health literacy and its association with non-communicable disease risk factors among retired Gurkha veterans in western Nepal

Health literacy strongly shapes health behavior and disease outcomes, yet little is known about it among retired veterans in low-resource settings. Retired Gurkha veterans of Nepal are one such ageing, underserved group, carrying a high burden of non-communicable disease (NCD) ri...

Risk-stratified versus standard-duration dual antiplatelet therapy after percutaneous coronary intervention: a systematic review and critical appraisal of prospective evidence

Guidelines endorse risk-stratification tools (DAPT score, PRECISE-DAPT, ARC-HBR) to individualise dual antiplatelet therapy(DAPT) duration after PCI, yet a fixed 12-month course still imposes a uniform ischaemic-bleeding trade-off on a heterogeneous population. To our knowledge,...

Can Childhood Longitudinal Cephalograms Predict Adult Facial Soft‐Tissue Dimensions? A Bayesian Modelling Study

ABSTRACT Introduction Predicting facial soft‐tissue growth is essential for treatment planning and long‐term outcome forecasting in orthodontics, orthognathic surgery and facial aesthetic surgery. This study evaluated whether longitudinal childhood cephalograms can predict adult...

Displaced people and kidney health

Purpose of review The number of displaced people worldwide continues to rise because of conflict and disasters-related crises. Kidney disease is increasingly recognized as an important contributor to morbidity among displaced populations, yet it remains under-prioritized in human...

Clinical characteristics and outcomes of patients with wild honey poisoning: a five-year retrospective study from Nepal

Wild honey poisoning caused by grayanotoxin-containing honey is an important toxicological emergency in the hilly and Himalayan regions of Nepal, where traditional consumption of wild honey remains common. However, systematic hospital-based data on its clinical presentation and o...