Bozhou People's Hospital

Palladium‐Catalyzed Cascade Carboesterification of Cycloalkenes With Alkynoic Acids: A Facile Access to Fused (E)‐Chloro‐Substituted γ‐Lactones

A palladium‐catalyzed regiodivergent carboesterification of cycloalkenes with alkynoic acids under aerobic conditions with ionic liquids as an environmentally benign medium is accomplished. Using a combination of 1 mol% IPr t Bu –Pd–Cin–Cl, 2 equiv. of LiCl in [Amim]BF 4 at rt fo...