Bnai Zion Medical Center

Cosmetic Appearance After Eye Loss: The Role of Prosthesis Motility and Eyelid Function

Background/Objectives: We aimed to clarify which clinical and prosthetic features are most strongly associated with cosmetic appearance after eye loss. Methods: This prospective cross-sectional study included 107 patients with unilateral anophthalmia wearing acrylic prostheses. E...

Brain Gadolinium Biodistribution, Clearance, and Retention Following High-Dose Contrast-Agent Exposure in Mice: A Multimodal Study

We evaluated gadolinium biodistribution, clearance, and long-term brain retention following high-dose gadolinium-based contrast agent (GBCA) exposure in 90 mice. Macrocyclic and linear agents were assessed using particle-induced X-ray emission (PIXE) alongside complementary eleme...

Gestational diabetes in multifetal versus singleton pregnancies: A multicenter cohort study

Abstract Introduction Gestational diabetes mellitus (GDM) is associated with increased neonatal morbidity in singleton pregnancies, but evidence in multifetal pregnancies is limited. Current diagnostic thresholds are largely extrapolated from singleton data; It remains unclear wh...

Failure to Fuse Shut Eyelids, a Novel Unique Sign in Affected Fetus with Homozygous PPP1R13L Pathogenic Variant—A Case Report and Review of the Literature

Prompted by a fetus with a homozygous PPP1R13L pathogenic variant and persistent open eyelids on sonography, suggesting fusion failure, this study marks the first prenatal human description linking PPP1R13L to eyelid closure, mirroring waved with open eyelids 2(woe2) and waved 3...

Clinical Meaningfulness and Improvement Thresholds of Myositis Core Set Measures: Association with Patient-Reported Outcomes

Objective The study aimed to evaluate the clinical meaningfulness and improvement thresholds of the myositis core set measures (CSMs) of disease activity in idiopathic inflammatory myopathies (IIM), emphasizing associations with patient-reported outcome measures (PROMs). Methods...