Blood Center of Zhejiang Province

Longitudinal Trajectories of the Atherogenic Index of Plasma and Their Associations with Clinical Outcomes After Transcatheter Aortic Valve Replacement

Background/Objectives: The atherogenic index of plasma (AIP) reflects atherogenic dyslipidemia, but the clinical relevance of its longitudinal patterns after transcatheter aortic valve replacement (TAVR) remains unclear. We aimed to characterize AIP trajectories and explore their...

S1P-TREM2 axis protects immunosuppressive neutrophils from ferroptosis to promote tumour progression in hepatocellular carcinoma

Background Neutrophils are increasingly recognised as immunosuppressive drivers of hepatocellular carcinoma (HCC), yet their persistence in the oxidative, lipid-rich tumour microenvironment remains poorly understood. Objective To elucidate the metabolic and molecular programmes t...

Characterisation of the Novel HLA‐DRB3*01:127 Allele by Next‐Generation Sequencing

HLA-DRB3*01:127 differs from the HLA-DRB3*01:01:02:01 allele by one nucleotide substitution in the exon 3.

Associations of C-reactive protein-triglyceride-glucose index and cholesterol-high-density lipoprotein-glucose index with heart disease risk in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: a cohort study from CHARLS

Abstract Background Although the C-reactive protein-triglyceride-glucose index (CTI) and cholesterol-high-density lipoprotein-glucose index (CHG) have both been implicated in adverse cardiovascular outcomes, their comparative predictive performance for incident heart disease amon...