Bionics Institute

Auditory- and Visual-Speech Evoked Activation of the Superior Temporal Gyrus Contralateral to the Cochlear Implant Predicts Speech Recognition Outcomes

Objectives: Speech recognition outcomes vary widely in cochlear implant recipients, but the reasons for this variability are not well explained by patient history factors alone. Neuroplastic reorganization after both deafness and cochlear implant switch-on can affect how new reci...

Multimodal Magnetic Resonance Imaging and Machine Learning Uncovers Distinct Progression Patterns in Friedreich Ataxia

Abstract Background Friedreich ataxia (FRDA) is a rare neurodegenerative disorder with heterogenous clinical progression, complicating prognosis and trial design. Neuroimaging offers objective biomarkers of disease progression, yet variability in progression patterns remains poor...

Recruitment of Aα/Aβ fibers during tonic electrical, optogenetic and combined stimulation in the mouse sciatic nerve

Abstract Background Neuromodulation of peripheral nerves via implanted devices produces relief from chronic pain in some patients, but rarely fully eliminates pain. Electrical stimulation lacks selectivity (e.g., between afferent and efferent fibers) to activate only the target A...