Biomedical Research and Innovation Institute of Cadiz

Multimodal Prodromal Patterns Associated with COPD Exacerbations in Home Telemonitoring: An Exploratory Observational Study

Characterizing multi-parameter physiological, acoustic, and environmental changes before acute chronic obstructive pulmonary disease exacerbations (AECOPD) is crucial for improving home telemonitoring and enabling timely clinical intervention. In a 12-month prospective observatio...

Device-Measured Physical Activity, Sedentary Time, and Cardiometabolic Risk Markers in Youth

Importance The evidence for benefits of higher physical activity and lower sedentary time on the cardiometabolic risk profile in youth is based on cross-sectional and small prospective studies. Objective To determine the prospective associations between device-measured physical a...

Factors associated with depression and anxiety in people who have suffered an acute myocardial infarction and undergone revascularization via percutaneous coronary intervention: a cross-sectional study

Acute myocardial infarction (AMI) is a cardiovascular event that has a significant clinical, functional, and emotional impact. Patients may experience anxiety and depression that could influence their recovery. This study aimed to identify the association between various biopsych...

Measurement Agreement and Reliability of the 6‐m Gait Speed Test in Adult Population: The ADULT‐FIT Project

We aimed to examine: (i) measurement agreement between photoelectric cell system and manual stopwatch timing; (ii) inter-rater agreement between trained and untrained raters using manual stopwatch timing; and (iii) reliability of the 6-m gait speed test to assess motor fitness in...

Longitudinal and reciprocal relationships between physical activity, physical fitness, executive functions, and arithmetic fluency in adolescents

Abstract Background The relationship between physical health and academic outcomes in adolescents is well-established, but the directionality and reciprocal nature of these associations remain unclear. Given the foundational role of mathematical skills in academic success, this s...

Natural and Hybrid Bioadhesive Polymeric Platforms for Bone Regeneration: A PRISMA-Guided Systematic Review of Design Strategies and Translational Challenges

Bone adhesives have long been pursued in orthopedic and regenerative medicine, but their clinical translation remains limited, particularly in wet and mechanically demanding environments. This PRISMA-guided systematic review analyzes bioadhesive biomaterials and adhesive regenera...

The diet supplemented with raw and hydrolyzed Microchloropsis gaditana and Arthrospira platensis blend modulates intestinal microbiota and metabolomic profiles in Sparus aurata

Abstract The transition toward sustainable aquaculture has prompted the search for alternative feed ingredients that support fish health while reducing dependence on fishmeal. Microalgae such as Microchloropsis gaditana and Arthrospira platensis are rich in bioactive compounds wi...

Mapping the Progression of Atrial Fibrillation Substrate: Insights from Left Atrial Wall Thickness and High-Density Voltage Mapping

Background/Objective: Advances in cardiac computed tomography (CT) now allow high-resolution, three-dimensional reconstruction of the left atrium, enabling precise quantification of left atrial wall thickness (LAWT). However, the relationship between LAWT and electrophysiological...

Malnutrition Severity, Morphofunctional Assessment, and Survival in Patients with Lung Cancer: A Multicentre Prospective Cohort Study

PURPOSE: Malnutrition is common in lung cancer and may contribute to impaired functional status and poor survival. This study evaluated the association between GLIM-defined malnutrition, morphofunctional nutritional parameters, and one-year mortality in patients with lung cancer....

Ruling In and Ruling Out Sepsis Using Likelihood Ratios of a Host Response Assay

Overview: SeptiCyte RAPID is an FDA-cleared gene expression test that quantifies host immune response to aid in the diagnosis of sepsis. The test yields a score (the SeptiScore) ranging from 0–15, distributed across four bands (1–4) based on increased likelihood of sepsis. Each b...