Bioinformatics Institute

Integrated metabolomics data analysis to generate mechanistic hypotheses with MetaProViz

ABSTRACT With the growing number of metabolomics and lipidomics studies, robust strategies for bioinformatic analyses are increasingly important. However, the absence of standardized and reproducible workflows, coupled with ambiguous metabolite annotations, hampers effective anal...

Robustness and cross-cohort concordance of developmental regulons in endometrial carcinoma

Claims about regulatory differences among endometrial carcinoma molecular classes must distinguish association, target-set robustness, and cross-cohort transportability. We evaluated a fetal Müllerian epithelial module and 20 prespecified developmental transcription-factor regulo...