Biodiversity Research Center, Academia Sinica

Unraveling the immune landscape and molecular signatures of antibody-dependent cellular cytotoxicity in SARS-CoV-2 clearance

Beyond direct neutralization, antibodies clear SARS-CoV-2 by triggering antibody-dependent cellular cytotoxicity (ADCC), which guides natural killer (NK) cells to eliminate infected cells. To understand ADCC’s role in COVID-19, we analyze samples from primary patients and find th...

Profiling maize embryonic leaf development and discovering new genes using high-resolution spatial long-read isoform sequencing

Abstract Profiling transcriptome isoforms in their spatial context is instrumental for deciphering plant embryogenesis. By combining high-throughput full-length isoform sequencing and spatial transcriptomics (spatial MAS-IsoSeq) in maize embryogenesis, we identified 285,639 isofo...

Baseline characterization of inshore reef soundscapes and noise dynamics along the southeast coast of South Africa

Underwater noise has risen in certain parts of the world, driven by continued growth of maritime economic activity. In South Africa, increasing economic development threatens to elevate underwater noise levels in marine habitats, yet knowledge of marine soundscapes remains very l...