Binzhou People's Hospital

AGDE-Net: a lightweight attention-guided dual-encoder network for tumor core and peritumoral edema segmentation in adult glioma

Abstract Background Glioma is a malignant primary brain tumor arising from glial cells, often resulting in fatal outcomes without timely treatment. Accurate and reliable tumor segmentation is essential for clinical decision-making and therapeutic evaluation. This study aims to de...

Lactylation and N6-Methyladenosine RNA modification in neuropsychiatric sequelae after intracerebral hemorrhage: a hypothesis-generating metabolic–glial–circuit framework

Depression, anxiety, cognitive impairment, fatigue, and sleep disturbance are clinically important sequelae of intracerebral hemorrhage (ICH), but the molecular events linking acute hemorrhagic injury to delayed neuropsychiatric vulnerability remain incompletely defined. This nar...

Robust 4f-2p-3d electron ladder for boosting the stability of oxygen electrocatalysis

Oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) are recognized as the core bifunctional catalytic processes in metal-air batteries, yet their inferior stability severely limits the large-scale deployment of these frontier devices. For resolving it, a bifunctio...

Machine learning identifies ac4C-related prognostic signature and TUBA1C as therapeutic target in COAD

To explore the role of N4-acetylcytidine (ac4C)-related genes (acRGs) in colon adenocarcinoma (COAD) and identify reliable prognostic biomarkers and potential therapeutic targets. Multi-source transcriptomic datasets (TCGA-COAD, GSE39582, GSE17536) and single-cell RNA-seq data we...

Lightweight structure-aware detection of coal and gangue under complex operating conditions

Accurate coal-gangue detection under complex operating conditions is crucial for reliable online perception in underground coal handling. To address degraded imaging, dense stacking, adhesion, and occlusion, this study proposes a lightweight structure-aware detector, LCGA-YOLO11,...

Nodular fasciitis of the nasal cavity with USP6 rearrangement: a case report

Nodular fasciitis (NF) is a benign myofibroblastic tumor characterized by rapid growth, self-limiting course, and rearrangement of the USP6 gene. While NF can occur in the head and neck region, cases originating within the nasal cavity are exceedingly rare. We herein report a cas...