Binghamton University

The Use of Clonidine in Patients With ADHD and Comorbid ODD

Background Attention-deficit/hyperactivity disorder (ADHD) co-occurs with oppositional defiant disorder (ODD), which lacks an approved treatment. Clonidine, an alpha-2 agonist approved for ADHD, is used off-label to target aggression, impulsivity, and hyperactivity, though eviden...

Enlicitide: The First Oral PCSK9i for Lowering Low-Density Lipoprotein Cholesterol

OBJECTIVE: This article describes pharmacology, pharmacokinetics, safety, and efficacy data of enlicitide, the first Food and Drug Administration (FDA)-approved oral proprotein convertase subtilisin/kexin type 9 inhibitor (PCSK9i). DATA SOURCES: PubMed, Embase, Web of Science, an...

Pharmacokinetic/pharmacodynamic evaluation of multidose oritavancin for prolonged durations of therapy

ABSTRACT Managing multidrug-resistant gram-positive infections is challenging, especially when prolonged therapy is needed for conditions like bacteremia, endocarditis, osteomyelitis, or other deep-seated infections. Oritavancin, a long-acting lipoglycopeptide, is increasingly us...

Mapping the Molecular Universe

Abstract The success of large-language-models highlighted the importance of datasets, whose quantity, quality, and diversity dictate the accuracy and creativity of artificial intelligence (AI) systems in learning and inferring. However, in scientific domains, such datasets requir...

Universalism and parasitic injustice

Abstract A common criticism of supposedly Enlightenment ideals is that, in the light of racial, gendered, and colonial injustice, they have never actually been universal. This article proposes a novel set of methodologies for testing the universalizability of normative ideals by...

Local-level refugee integration within a context of multi-level governance: Turkey in comparative perspective

Refugee integration is a multi-level governance (MLG) issue in which municipalities play a central yet constrained role. This article asks under what conditions the downward shift of responsibility for refugee integration to municipalities yields local capacity. It argues that th...

Measurement Entropy and Conditional Information in Time-Reversed Young Interferometry

Time-reversed Young (TRY) interferometry holds a detector channel fixed while a source coordinate is scanned or programmed. We describe this measurement through a single accepted source–detector probability law obtained from scalar Fresnel propagation, the programmed source prior...

Mental Health in Regularly Collected Nationally Representative U.S. Surveys: What’s Measured and What’s Missing?

Abstract To document the availability and quality of mental health measures in regularly collected national surveys in the United States. We conducted a review of the mental health measures included in eight publicly available health-focused recurring surveys capable of producing...

Embeddings into highly transitive and mixed identity free groups

Given a countable group G , we develop a method to construct an overgroup H that is finitely generated, highly transitive and mixed identity free. Our construction can be controlled to ensure that some fundamental group theoretic properties of G are inherited by H , such as amena...

Post-Post-API Age: Studying Digital Platforms in Scant Data Access Times

Over the past decade, data provided by digital platforms has informed substantial research in HCI to understand online human interaction and communication. Following the closure of major social media APIs that previously provided free access to large-scale data (the “post-API age...

Predictors of perceived value of multi-cancer early detection testing: a national PRECEDE–PROCEED framework study

Abstract Background Multi-cancer early detection (MCED) tests present a paradigm transform in cancer screening by detecting multiple cancer types from one blood sample. While studies have shown high levels of public interest in MCED screening, little is known about factors shapin...

A walk down memory lane: How memories influence stock investment and information processing

Propensity to invest in stocks is highly heterogeneous, with many households avoiding stock market participation altogether. This heterogeneity is difficult to reconcile with standard economic theory. We study the role of memories in shaping investment decisions and in influencin...

Liquid Metal Nanoparticle‐Coated Endospores as Dormant‐to‐Active Bioelectrocatalysts for Microbial Power

ABSTRACT A central ambition of engineered living materials is to exploit the dynamic behaviors of living cells, yet the synthetic interfaces that make them useful are typically static. When a cell changes shape and physiological state, rigid coatings crack while weakly bound ones...

Air Pollution, Anemia and Nutrition: A Scoping Review of Research Gaps in the Role of Nutrients in PM2.5-Related Anemia

Anemia, a major global public health issue, has been increasingly linked to air pollution. Growing evidence suggests that fine particulate matter (PM2.5) exposure is associated with reduced hemoglobin concentrations and increased anemia risk, potentially through pathways involvin...

Bacterial extracellular vesicles as players in biofilm dynamics and community interactions

The ability to use vesicles to deliver cargo safely across distance is a valuable strategy that appears to be universal across all life. The ability of prokaryotes to accomplish this is a relatively new idea, but one that is expanding rapidly. In this review, we will describe wha...

Uncertainty-aware model-enhanced soft actor-critic for conformal coating parameter optimization

Abstract Conformal coating optimization requires control of multiple application parameters to achieve target thickness and coverage uniformity, with spray atomization settings (atomization valve control) playing a crucial role in droplet formation and material deposition. Tradit...

Election delay: public support for postponing elections during public health crises

Is it democratic to postpone elections under an emergency situation? Considering the fact that 80 countries around the world postponed elections, this study takes a rare look at citizens’ attitudes toward election delay during a crisis time (the COVID-19 pandemic). Using national...

From alliance to adversary: regional parties and the challenges of federal crisis management during the COVID-19 pandemic

Abstract This paper explores how political incentives shape the balance between decentralization and centralization in federal crisis policymaking. Building on second-generation fiscal federalism, it conceptualizes crisis responses as strategic choices rather than fixed instituti...

Faradaic and Non-Faradaic Spectral Induced Polarization Signatures of Copper and Graphite Mixtures: Disseminated Grain Versus Veinlet Mineral Structures

Summary Characterizing electronically conductive minerals with spectral induced polarization (SIP) has been a longstanding goal of mineral exploration. A more comprehensive understanding of how mineral texture (e.g. disseminated grain versus veinlet forms) and mineral type influe...

Don’t Take Their Word for It: Reply to Fan

Abstract In my (2024), I argued that there are principled reasons for thinking that AI cannot be an authority about one’s own mind. The idea is that it is only rational to treat another as an epistemic authority under certain conditions, and AI does not meet one of those conditio...