Bielefeld University

Tumor Necrosis is Associated with an Increased Metastatic and Cardiovascular Risk in Paragangliomas: A Single-Center Series and Meta-Analysis Comparing Necrosis and Cystic Degeneration in Paragangliomas

Abstract Paragangliomas (PGLs) are rare neural crest–derived tumors with highly variable morphology and clinical behavior. These tumors can present with cystic and necrotic alterations that may influence the clinical presentation of affected patients. However, prevalence and clin...

From Product-Quality Complaints to Patient-Safety Triage: A Structured Narrative Review and Proposed PRCS-TRACE Framework

Product-quality complaints are usually handled as pharmaceutical quality-system events, yet defects in sterility, potency, identity, packaging, labelling, storage, distribution or delivery-device function may affect medication use, treatment continuity and patient outcomes. This...

A multilevel analysis of the predictive effects of internal migration and region of residence on women’s empowerment in Nigeria

BACKGROUND: Despite growing research interest on the influences of migration and regions of residence on human behaviors, studies on the influences of migration and region of residence on women empowerment especially in sub-Saharan Africa are lacking. Thus, this study investigate...

Tribenzotriquinacene Fused Dimers (“Fusodimers”)—Synthesis and Host–Guest Properties

ABSTRACT The synthesis and structural properties of two stereoisomeric tribenzotriquinacene (TBTQ) derivatives, syn ‐ 4 and anti ‐ 4 , in which two rigid TBTQ bowls share a common benzene ring, are described. Owing to the orthogonal orientation of the three indane wings in each o...

Can parent–child interactions help reduce socioeconomic differences in language development? Results of a German birth cohort study

Abstract Aim Children from socioeconomically disadvantaged families often have lower developmental outcomes than their socioeconomically more advantaged peers. In early childhood, language development (LD) in particular is a key competence for further socialization. There is a ne...

Shifting AAV9 tropism by binding moiety insertion enhances transduction of tumor cell lines and human glioblastoma explants

Abstract Tumor-specific targeting remains a major obstacle for the development of precision cancer therapies. For several tumors and specifically glioblastoma (GBM), an aggressive brain tumor with poor prognosis, more effective treatments are urgently needed. Recombinant adeno-as...

Crossing effects in the tactile temporal order judgment task: a meta-analysis

Abstract The tactile temporal order judgment (TOJ) task is widely used in multisensory neuroscience. Participants judge which of two tactile stimuli, one on each hand, came first. A key finding is that TOJ performance declines when the arms are crossed, likely due to interactions...

The Moment of Delivery in Online Retailing: How Courier Types and Inoculation Messages Affect Reactions to the Last-Mile Experience

Online customers’ journeys span several touchpoints, which typically do not involve any interpersonal interactions with online retailers—except at the moment of delivery (MoD). When retailers use third-party courier services to fulfill orders, they relinquish control over this cr...

Measures to Identify Gifted Students in STEM Subjects: A Systematic Review of Literature

Models of giftedness describe various factors related to its expression. Using measures with established psychometric quality can help teachers identify gifted students. In this systematic review, we analyzed developmental studies on measures to identify gifted students in scienc...

From Perceptrons to Convolutional Neural Networks: A Practical Tutorial on Spatial Deep Learning

This tutorial takes the reader on a historical and technical journey from the simple Perceptron (1958) to modern Convolutional Neural Networks (CNNs) that dominate spatial data processing (images and video). We start with the Perceptron’s linear classifier, then expose its inabil...

What law students need

Abstract This paper explores the specific expectations and needs of law students with regard to an introductory Python course tailored to their unique academic and professional requirements. The study involved semi-structured interviews with law students at the University of Mann...

Ruling In and Ruling Out Sepsis Using Likelihood Ratios of a Host Response Assay

Overview: SeptiCyte RAPID is an FDA-cleared gene expression test that quantifies host immune response to aid in the diagnosis of sepsis. The test yields a score (the SeptiScore) ranging from 0–15, distributed across four bands (1–4) based on increased likelihood of sepsis. Each b...