Ben-Gurion University of the Negev

P1.151. Management of Antral Adenocarcinoma 14 Years After Esophagectomy With Gastric Pull-Up: A Surgical Challenge

Abstract Topic Esophageal Cancer: Other Case Submission An 84-year-old male had previously undergone a three-field esophagectomy with gastric pull-up reconstruction for stage I adenocarcinoma of the distal esophagus 14 years earlier. He remained disease-free during long-term foll...

Biogeochemical dichotomy and intra-order variability in Miliolid and Rotaliid foraminifera

Abstract. Foraminiferal geochemical records reflect both environmental and biological influences. Disentangling these factors is essential for improving their application in marine monitoring and contributing valuable insights into the evolution across major foraminiferal lineage...

Individualized Prediction of Recurrence Following Uterine-Preserving Pelvic Organ Prolapse Repair Using Internally Validated Machine Learning Models

Background/Objectives: Approximately 11–20% of women affected by pelvic organ prolapse (POP) will undergo surgical intervention during their lifetime and nearly one-third of these women will require an additional procedure due to recurrence or failure of the initial repair. This...

Joint-RPCA: domain-aware multi-omics integration for systems microbiology

Integrating multi-omics data is essential for microbiome research, as microbial communities are shaped by and respond to interdependent processes, including taxonomic composition, metabolite production and utilization, and gene expression. However, accurately capturing ecosystem-...

Putting Globus Into Context: Prevalence, Characteristics, and Overlap With Other Disorders of Gut‐Brain Interaction

OBJECTIVE: Globus is characterized by the sensation of a lump in the throat without dysphagia or underlying structural abnormality or major motility disorder. Reported prevalences vary considerably across studies. Globus has been linked to both heartburn and affective disorders....

Development and internal validation of the Low Cardiac Index Score: a simplified bedside tool for continuous intraoperative screening

<title>Abstract</title> Purpose Advanced haemodynamic monitoring of cardiac index is restricted to selected high-risk cases, leaving most patients undergoing major surgery without real-time assessment. We aimed to develop and internally validate a simplified bedside score for con...

A protein chaperone can stabilize the intein‐containing precursor to indirectly promote protein splicing

Abstract In tervening pro teins (inteins) interrupt host protein sequences and are removed by a self‐mediated protein splicing reaction. Inteins are abundant in the microbial world and are often found within essential genes involved in DNA replication, recombination, and repair....

Biosynthesis and Genetic Tuning of Guanine Crystals via Metabolic Engineering of Yeast

ABSTRACT Purine crystals, such as guanine, generate diverse optical phenomena in animals and function as important nitrogen‐storage reservoirs in microalgae. Here, we demonstrate the formation of guanine crystals in Brewer's yeast. Whilst guanine crystals do not naturally contrib...

Knowledge design in complex domains

Traditional Knowledge Engineering (KE) often fails to address modern complex domains characterized by "wicked problems," where non-stationary ground truths and high dimensionality render static rule sets obsolete. This paper proposes a paradigm shift from traditional Knowledge En...

Fostering reflection: Development and initial evaluation of a mentalization-based GenAI simulator for foster care supervisors

Background Foster care supervisors require advanced reflective functioning (RF) to manage complex relational demands, yet traditional training is difficult to scale and access. Generative AI (GenAI) may help by enabling simulated practice environments. Objective This feasibility...

Evaluation of a 3D Crustal Velocity Model for Northern Israel Using Wavefield Simulations

ABSTRACT We evaluate a recently developed 3D crustal velocity model for northern Israel using numerical simulations of seismic wave propagation for eighteen earthquakes (3≤Mw≤4.5). Synthetic seismograms were compared with observed recordings from the Israel Seismic Network in the...

Volunteering and resilience in wartime: evidence from two population-based studies in Israel

Abstract Background Resilience is a key factor in coping with and recovering from large-scale traumatic events. Although volunteering has generally been associated with improving or maintaining resilience, evidence from wartime contexts is mixed. This study examined the associati...

Corpus callosum fractional anisotropy from routine diffusion tensor imaging predicts dementia in older adults beyond clinical risk factors

Dementia arises from multifactorial neurodegenerative processes, with growing evidence implicating blood-brain barrier dysfunction, neuroinflammation, and vascular injury as contributors to progressive brain tissue damage. Because decline in white matter microstructural integrity...

Rewetting pulses, more than soil properties, control nitrogen losses from drought-stressed agroecosystems

Climate change is intensifying drought–rewetting cycles in Mediterranean drylands, yet their interactive effects with soil texture on agricultural trace gas emissions remain poorly understood. We conducted a year-long rainfall manipulation experiment using co-located soils of thr...