Beike Biotechnology (China)

Large-scale proteomic characterization reveals clinically relevant subtypes of early-stage papillary thyroid cancer for prognostic prediction

Papillary thyroid cancer (PTC) has a rising incidence. The majority are diagnosed at an early stage, albeit with a minority exhibiting aggressive tendencies. Given its generally indolent nature, controversy persists regarding the management of early-stage PTCs, particularly surgi...

Methyl indole-3-acetate contributes to strain-specific anti-inflammatory effects of Lactiplantibacillus plantarum

Lactiplantibacillus plantarum is a widely recognized probiotic with anti-inflammatory potential, yet its efficacy varies among strains and the underlying determinants remain poorly defined. Here, we identify methyl indole-3-acetate (MIA), a previously uncharacterized microbial me...

Development of a multiplex real-time PCR assay with fluorescence probe-melting-curve analysis for one-tube detection of respiratory pathogens

Pathogens causing respiratory infections have reemerged globally since the COVID-19 pandemic. Rapid and accurate identification of respiratory pathogens is critical for diagnosis and treatment. In this study, we developed and evaluated a multiplex real-time PCR assay with a fluor...