Beijing VDJBio (China)

Star polycation nanocarrier selectively enhances mesotrione control efficacy via reduced particle size and improved foliar absorption

Abstract BACKGROUND Nanocarrier‐based formulations offer a superior means of enhancing control efficacy and increasing utilization. Star polycation (SPc) was an efficient nanocarrier of insecticides and fungicides. However, whether it could serve as an herbicide nanocarrier needs...

Extracellular vesicle proteins monitor and interfere with CLDN18.2-targeted CAR-T cell and antibody therapies against gastrointestinal cancers

Abstract Claudin 18.2 (CLDN18.2)-targeted CAR-T cell and antibody therapies show promise against gastrointestinal cancers, but biomarkers predictive of long-term benefit and therapeutic sensitization strategies are needed. Here we show that proteins carried by circulating extrace...

Ganoderic Acid A Reverses Ultraviolet B Induced Hyperpigmentation via Multi-Targeted Regulation of Mitochondrial Homeostasis and Inflammation

Background: Conventional tyrosinase (TYR) inhibitors irritate skin and trigger rebound pigmentation, necessitating safer and more effective depigmenting agents. Methods: Biocompatibility was assessed by cell viability. Melanin content and TYR activity were measured spectrophotome...