Beijing Proteome Research Center

The lung–brain axis and neuroinflammation: a convergence model and the role of exercise

Pulmonary and neurological disorders are increasingly recognized as interconnected manifestations of systemic neuroimmune dysregulation mediated by the lung–brain axis. Diverse pulmonary insults, including acute respiratory distress syndrome, chronic obstructive pulmonary disease...

MINK1 inhibition suppresses triple-negative breast cancer by abrogating ALDOA S39 phosphorylation and reprogramming glucose metabolism

Triple negative breast cancer (TNBC) represents the most malignant subtype of breast cancer, with heightened invasiveness, frequent recurrence and poor prognosis. Deciphering the molecular mechanisms underlying TNBC pathogenesis and drug resistance is critical for developing prec...