Beijing Obstetrics and Gynecology Hospital

Accelerometer-measured moderate-to-vigorous physical activity patterns and mortality among individuals with venous thromboembolism: a prospective cohort study from the UK Biobank

Although the “weekend warrior” activity pattern has been associated with lower mortality in the general population, whether it is associated with long-term outcomes after venous thromboembolism (VTE) remains unclear. In this prospective analysis, we examined the association betwe...

Association of inflammatory biomarkers and pericoronary fat attenuation index with coronary functional ischemia in patients with metabolic dysfunction-associated fatty liver disease

Patients with metabolic dysfunction-associated fatty liver disease (MAFLD) and coronary heart disease (CHD) exhibit systemic and coronary inflammation. However, the value of integrating systemic inflammatory biomarkers and the pericoronary fat attenuation index (FAI) for identify...

Clinical risk factors and protective factors of preeclampsia in China

The pathophysiology of preeclampsia remains unclear. The identification of risk factors and protective factors may help elucidate the pathophysiologic basis of preeclampsia and improve its prediction. A cross-sectional survey of all deliveries in 39 hospitals across 14 provinces...

Vaginal Cuff Length and Time to Postoperative Stump Recurrence After Hysterectomy for Cervical Cancer: An Exploratory Single-Institution Study

Backgroud/Objectives: In this exploratory study, we explored the relationship between the timing of recurrence and vaginal cuff length (VCL) in patients with vaginal stump recurrence after hysterectomy. Methods: This is a single-institution study which included 25 consecutive pat...

APEX1 deficiency impairs oocytes quality by disrupting mitophagy and activating ferroptosis in diminished ovarian reserve

Diminished ovarian reserve (DOR) is pathological condition characterized by reduced oocyte quantity and quality. Due to the complex etiology and limited therapeutic options, clarifying the underlying molecular mechanisms is critical. Oxidative stress has emerged as a pivotal cont...

Fuzuloparib in combination with apatinib versus fuzuloparib alone for recurrent ovarian cancer: a randomized, open-label, phase 2 trial

A randomized, open-label, phase 2 trial assessed fuzuloparib (a PARP inhibitor) plus apatinib (a vascular endothelial growth factor receptor [VEGFR] inhibitor) versus fuzuloparib alone in patients with recurrent ovarian cancer (ROC). Patients with ROC who had failed ≥ 2 lines of...

Vision-Language Model as a ‘Zero-Shot’ Assistant for Evaluating Condylar Osseous Changes in Cone-beam Computed Tomography

INTRODUCTION AND AIMS: Interpreting condylar osseous changes on CBCT is challenging for general practitioners. This study evaluated the 'zero-shot' diagnostic performance and utility of Vision-Language Models (VLMs) as AI assistants for detecting condylar abnormalities. METHODS:...

Comprehensive genomic characterization of extraintestinal pathogenic Escherichia coli isolated from neonates: multiple center insights into virulence, resistance, and transmission dynamics

Neonatal extraintestinal pathogenic Escherichia coli (ExPEC), which can cause severe long-term sequelae by systemic infections, is gradually becoming the primary pathogen threatening neonatal health. The lack of large-scale genomic epidemiological investigation hinders further un...

Factors associated with venous thromboembolism in ICU patients with sepsis: A retrospective analysis using the MIMIC-IV database

This study used the MIMIC-IV v3.1 database to examine factors associated with venous thromboembolism (VTE) in adult ICU patients with sepsis, excluding those with prior VTE or ICU stays under 48 h. Among 14,784 eligible patients, 1,038 (7.0%) developed VTE during their ICU stay....