Beijing Institute for Stem Cell and Regenerative Medicine

Integrated metabolomic and targeted lipidomic profiling reveals systemic metabolic dysregulation in the follicular microenvironment of polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is a prevalent endocrine and metabolic disorder that significantly impacts female fertility. The follicular microenvironment, particularly follicular fluid (FF), plays a critical role in oocyte development, yet the systemic metabolic dysregulation...