Baylor Scott & White Health

Caspase-3 dependent, induction of barrier dysfunction and hyperpermeability in blood-brain barrier endothelial cells

BACKGROUND: Blood-brain barrier (BBB) dysfunction and associated microvascular hyperpermeability lead to brain edema and elevation of intracranial pressure in traumatic and ischemic brain injuries. Pro-inflammatory cytokines, interleukin (IL-1β) and tumor necrosis factor (TNF-α),...

Genicular artery embolization for symptomatic knee osteoarthritis: A narrative review

Knee osteoarthritis (KOA) is a highly prevalent and debilitating condition associated with substantial physical, psychological, and socioeconomic burden. For patients in whom conservative therapy has failed and who are unable or unwilling to undergo arthroplasty, treatment option...

History of worsening heart failure and outcomes with vericiguat in ambulatory HFrEF: an exploratory post-hoc analysis of VICTOR

Stefan Störk, Javed Butler, Caroline Morbach, Fabian Kerwagen, Johann Bauersachs, Ephraim B Winzer, Justin Ezekowitz, Carolyn S P Lam, Inga Bayh, Stefan He

Artificial Intelligence predicted ESC 2026 Heart Failure Guidelines

Guillaume Baudry, MD, PhD, Javed Butler, MD, MPH, MBA, Faiez Zannad, MD, PhD; Artificial Intelligence predicted ESC 2026 Heart Failure Guidelines, European