Baotou Medical College

Joint associations of triglyceride-cholesterol-body weight index and glycated hemoglobin with incident diabetes: a prospective study from the CHARLS cohort

Abstract Introduction The triglyceride–cholesterol–body weight index (TCBI) integrates lipid metabolism and adiposity, whereas glycated hemoglobin (HbA1c) reflects long-term glycemic status. However, their joint association with incident diabetes remains unclear. This study exami...

Association between respiratory phenotypes and successful ventilator liberation in early-onset and late-onset ARDS: a multicenter cohort study

Early-onset and late-onset acute respiratory distress syndrome (ARDS) differ in clinical course and outcomes, but their longitudinal respiratory trajectories remain unclear. We aimed to characterize respiratory trajectories in early- and late-onset ARDS and identify trajectory-ba...

Silicon Nitride Nanofilm Functionalized Titanium Mesh for Boosting Osseointegration by Macrophage-Related Immunomodulation

Abstract Titanium mesh-supported guided bone regeneration (TM-GBR) has emerged as a clinically effective strategy for alveolar bone augmentation in complex defects, primarily through its ability to preserve osteogenic space and correct bone volume deficiencies. However, due to th...

Ring chromosome 7 syndrome with severe hypertriglyceridemia and mild echocardiographic abnormalities: a case report

Abstract Background Ring chromosome 7 [r(7)] is an extremely rare constitutional chromosomal abnormality. The most frequently reported features include growth retardation, pigmented skin lesions, and microcephaly. However, the full phenotypic spectrum remains incompletely defined...

Gut microbiota‑driven indole‑3‑propionic acid protects against sepsis‑associated encephalopathy via inhibiting BNIP3L ubiquitination and restoring BNIP3L‑dependent mitophagy as a potential molecular mechanism

Sepsis-associated encephalopathy (SAE) is a severe refractory neurological complication occurring in up to 70% sepsis patients with no targeted therapies. Gut microbiota-derived indole-3-propionic acid (IPA), a tryptophan metabolite, exerts neuroprotective effects, but its therap...

Solitary Intraosseous Neurofibroma of the Mandible: A Case Report

Abstract Background Solitary intraosseous neurofibroma of the mandible is a rare benign peripheral nerve sheath tumor. Owing to its low incidence and nonspecific clinical and radiographic features, diagnosis can be challenging. We report a rare case with extensive mandibular dest...

Pan-cancer characterization of PAFAH1B3 expression and its role in esophageal cancer

Globally, esophageal cancer is one of the main reasons of deaths from cancer. The initiation and progression of this malignancy is the result of complex interactions between alterations in genes, epigenetic processes and components of the tumor microenvironment. Esophageal squamo...

Synchronous gastric-type intraepithelial neoplasia and ectopic pancreas in the gastric antrum diagnosed by en bloc endoscopic submucosal dissection: a case report and literature review

Ectopic pancreas is a relatively common submucosal lesion of the stomach and is generally considered benign. Emerging evidence, however, suggests that ectopic pancreas may coexist with synchronous neoplastic changes of the overlying gastric mucosa. Because submucosal protrusions...

Clinical application of artificial intelligence technology in epilepsy

Epilepsy is a prevalent neurological disorder, and its inherent complexity and significant interindividual variability pose substantial challenges for clinical diagnosis and treatment. Against this backdrop, the rapid development of artificial intelligence (AI) technology is driv...