Baotou Central Hospital

Organ-specific biological age gaps show heterogeneous and direction-dependent genetic relationships with age-related diseases

Organ-specific biological age gap (BAG) traits are model-derived measures of ageing-related variation, but their genetic relationships with age-related diseases and the genomic scale of these relationships remain unclear. We analysed European-ancestry genome-wide association stud...

Features and a specific pattern of cerebral perfusion in patients with Lewy body dementia: Diagnostic ability and clinical correlations

Cerebral perfusion changes have been observed in patients with both dementia with Lewy bodies and Parkinson’s disease dementia. In this study, features of cerebral blood flow (CBF) and a specific perfusion pattern measured using arterial spin labeling (ASL) MRI for Lewy body deme...

Efficacy, safety, and pharmacokinetics of pumecitinib nasal spray for moderate-to-severe seasonal allergic rhinitis: a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial

Background Seasonal allergic rhinitis (SAR) is a pollen-triggered condition causing nasal inflammation and quality of life impairment. Pumecitinib, a topical Janus kinase (JAK) inhibitor may modulate allergic inflammation. We evaluated the efficacy, safety, and pharmacokinetics o...

Clinical application of artificial intelligence technology in epilepsy

Epilepsy is a prevalent neurological disorder, and its inherent complexity and significant interindividual variability pose substantial challenges for clinical diagnosis and treatment. Against this backdrop, the rapid development of artificial intelligence (AI) technology is driv...