Bahawal Victoria Hospital

Effect of SGLT2 inhibitors on arrhythmic and device-therapy outcomes in heart failure patients with ICD/CRT-D: a systematic review and meta-analysis

Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) improve heart failure outcomes, but their association with arrhythmic events and device-therapy endpoints in patients with implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy-defibrillator...

Myocardial Fibrosis in Pediatric Heart Disease

Myocardial fibrosis is increasingly recognized as a central determinant of adverse cardiac remodeling and long-term cardiovascular outcomes in children with congenital and acquired heart disease. Once considered an irreversible consequence of chronic myocardial injury, fibrosis i...

Comparative efficacy and safety of oral iron polymaltose complex vs. ferrous sulphate in the treatment of pediatric iron deficiency anemia: a systematic review, meta-analysis and trial sequential analysis

Oral iron supplementation is the first-line therapy for pediatric iron deficiency anemia (IDA). Ferrous sulphate (FS) remains the conventional standard of care but frequently induces gastrointestinal (GI) adverse effects. Iron polymaltose complex (IPC) has emerged as an alternati...

Left Atrial Myopathy as a Phenotypic Axis in HFpEF: Implications for Pulmonary Hypertension, Exercise Intolerance, and Targeted Therapy

Heart failure with preserved ejection fraction (HFpEF) is a highly heterogeneous syndrome characterized by impaired ventricular relaxation, systemic inflammation, and multisystem cardiovascular dysfunction. Despite growing recognition of HFpEF as a major global health burden, eff...

Mixed phenotype acute leukemia mimicking adult-onset Still’s disease in a pregnant female: A rare case report

Introduction: Mixed phenotype acute leukemia (MPAL) is an uncommon hematologic malignancy characterized by the coexistence of lymphoid and myeloid lineage markers. Although adult-onset Still’s disease (AOSD) is a diagnosis of exclusion, MPAL may rarely present with similar labora...