Babol University of Medical Sciences

Stress, coping styles and social support in patients with thalassemia: a case–control study

Thalassemia is an inherited blood disorder associated with numerous challenges for individuals. The aim of this study is to compare the levels of perceived stress, coping strategies, and social support among individuals with thalassemia and healthy individuals. In this case–contr...

Machine-learning models for Alzheimer’s disease classification using routinely available clinical, cognitive, and neuropsychiatric variables

Alzheimer’s disease (AD) is the most common cause of dementia. Although machine-learning models have shown promise for AD classification, many approaches rely on neuroimaging, biomarker assessments, or extensive neuropsychological evaluations that are not routinely available in c...

Sex-specific associations of ACE2 variants with COVID-19 hospitalization, viral load, and mortality: an Iranian hospital-based case-control study

Abstract Angiotensin-converting enzyme 2 ( ACE2 ) is the cellular receptor for SARS-CoV-2, and its genetic polymorphisms may influence COVID-19 susceptibility. This hospital-based case-control study investigated the association between three ACE2 SNPs (rs2285666, rs4646127, rs971...

A Bayesian network analysis of the association between quality of life and burnout among nurses in Iran

Burnout and reduced quality of life are prevalent and interrelated issues among nurses, especially in high-stress healthcare settings. This study applies Bayesian network analysis to examine the association between quality of life and burnout among nurses in Iran by identifying k...

Urinary incontinence and its association with physical and sexual activity in older women: a population-based cross-sectional study

Urinary incontinence (UI) is a common but neglected health problem in older women, and its association with physical and sexual activity remains uncertain. This study aimed to assess this association in older women participating in the Amirkola cohort study. This secondary cross-...

Elucidating an explanatory model for cancer care management within the urban family physician setting in Iran: a qualitative grounded theory study

Cancer care management requires coordinated and continuous services across prevention, diagnosis, treatment, and supportive care pathways. Despite ongoing efforts to strengthen primary healthcare in Iran, an integrated framework explaining how cancer care can be organized within...

Complex perineal impalement with combined bladder and ileal injury following transpelvic penetration: a case report

Abstract Background Perineal impalement injuries are uncommon yet clinically significant due to their complex diagnostic and therapeutic challenges, especially when involving adjacent visceral components, such as the bladder and small intestine. Early recognition and a multidisci...

Trend analysis of breast cancer screening in Golestan province’s family physician program: performance evaluation for women aged 30–69

In the ranking of cancer incidence for the year, female breast cancer was the most common cancer in the north-east region of Iran. This study aimed to comprehensively evaluate the trend of breast cancer screening within Golestan province’s Family Physician Program. This repeated...

Complications of repeated transradial artery access for coronary angiography: a prospective cohort study

Radial artery access is preferred for coronary angiography due to reduced bleeding risk and faster recovery; however, the safety of repeated access through the same artery remains uncertain. This study aimed to describe the incidence of complications including occlusion, spasm, a...

The Effect of Ceratonia siliqua (Carob) on Male Infertility: A Systematic Review and Meta-analysis of invitro and randomized controlled trials.

Oxidative stress is a key contributor to impaired se-men quality in male infertility. Ceratonia siliqua L. (car-ob), a polyphenol-rich plant traditionally used to improve male fertility, has been investigated as a potential in-tervention for improving semen parameters and repro-d...

Childbearing attitudes and associated factors among married couples in Mazandaran Province, Iran: a cross-sectional study

Abstract Background Childbearing attitudes are influenced by various demographic, socioeconomic, and psychosocial factors. This study aimed to examine factors associated with childbearing attitudes among married couples in Mazandaran Province, Iran. Methods A cross-sectional anal...

Downregulation of miR-223 in a cyclophosphamide-induced mouse model of premature ovarian failure: histological and hormonal correlations

Premature ovarian failure (POF) is characterized by early ovarian dysfunction leading to infertility and hormonal imbalance. microrna-223 (MiR − 223) is a key microRNA that regulates multiple cellular processes, including inflammation, apoptosis, and follicular development. Emerg...

Feedback loops as a core driver: rethinking organizational readiness for knowledge translation in Iranian medical universities

Bridging the gap between research evidence and healthcare decision-making, knowledge translation (KT) is a critical process. However, despite advances in research production, many universities in low- and middle-income countries face significant challenges in implementing KT due...

An integrated overview of acute heart failure: a narrative review of pathophysiological mechanisms and contributing factors

Abstract Background Acute heart failure (AHF) is a significant cardiovascular syndrome characterized by either new-onset heart failure (HF) or acutely decompensated heart failure (ADHF), typically presenting with systemic and pulmonary congestion. The European Society of Cardiolo...

Factors affecting the quality of education in clinical and academic settings from the perspective of stakeholders: a qualitative study

Purpose Quality education is critical to developing competent human resources in clinical settings. Identifying the factors that influence educational quality can help improve educational programs. This study, conducted at X University of Medical Sciences, aims to explain these f...

Nutritional literacy as a potential moderator of the intrinsic capacity–frailty relationship in older adults: a cross-sectional study

Abstract Intrinsic capacity (IC) and frailty are two interrelated constructs that shape the functional trajectory of aging. Although both are influenced by multiple lifestyle and health-related factors, limited evidence exists on how nutritional literacy (NL), the nutrition-speci...

Motor control exercises with and without the McKenzie method of mechanical diagnosis and therapy for fear-avoidance beliefs in chronic low back pain: a two-arm, parallel-group superiority randomized controlled trial protocol

Chronic low back pain (CLBP) is a major cause of disability and is commonly associated with psychological factors such as fear-avoidance beliefs and reduced pain self-efficacy. Motor control exercises aim to improve spinal stability, while the McKenzie method of mechanical diagno...

Cervical cytological abnormalities and human papillomavirus status in HPV-vaccinated and unvaccinated women: a cross-sectional study

To investigate the association between HPV vaccination status and cervical cytological findings, HPV prevalence, and genotype distribution among Iranian women, providing real-world evidence from a population with limited epidemiological data. A cross-sectional study was conducted...