Azienda Sanitaria Locale Roma 3

Augmenting colonoscopy with artificial intelligence and robotic assistance: a human-factors scoping review toward a task-based shared autonomy paradigm

Colonoscopy is central to colorectal cancer prevention but remains a high-demand psychomotor and cognitive procedure, characterized by operator dependency, variable performance, and substantial physical and mental workload. Increasing evidence links procedural quality and safety...

Medication Complexity and Insomnia Severity in Psychiatric Outpatients: A Moderation Analysis Across Mood and Non-Mood Disorders

Background: Insomnia is common and occurs across psychiatric diagnoses. A prior analysis of this outpatient cohort found that psychotropic medication complexity was associated with insomnia severity, but whether this association is stronger in particular diagnostic groups was not...

Patient Satisfaction and Perceived Stress in Digestive Endoscopy

OBJECTIVE: To evaluate patient satisfaction and perceived stress among adults undergoing diagnostic digestive endoscopy in Italy and to examine their associations with sociodemographic, clinical, and procedural factors. BACKGROUND: Patient satisfaction is a key indicator of endos...

Horizon Scanning of Multiple Sclerosis Expenditure in Italy (2025–2029): Updated Insights from the Oracle Model

Multiple sclerosis (MS) is a chronic and progressively disabling neurological disease associated with a substantial clinical and socioeconomic burden. The introduction of an increasing number of new innovative therapies has further intensified concerns regarding the long-term sus...

The rising burden of scabies in Italy: insights from a nationwide survey of dermatologists

BACKGROUND: Scabies is an increasingly relevant dermatological and public health issue, with rising case burdens reported in several European countries. OBJECTIVES: To assess Italian dermatologists' perceptions of recent scabies trends and current approaches to diagnosis, treatme...

The indolent nature of gastroblastoma. Report of an illustrative case with 28 years of follow-up showing previously unreported immunohistochemical and molecular features

We report the clinical, morphological, ultrastructural, and molecular features of a gastroblastoma diagnosed in a 27-year-old male describing some unreported findings that can help to better understand this very rare tumor. The clinical course lasting 28 years confirms the indole...

Long-term outcomes and treatment cost estimates of flavonoids and polidocanol foam sclerotherapy for hemorrhoidal disease: a retrospective cohort study

Abstract Background Flavonoids and sclerotherapy are first-line treatments for hemorrhoidal disease (HD), but direct comparisons of long-term outcomes, patient satisfaction, and economic estimates are limited. Methods This single-center retrospective study included consecutive pa...

Effects of heat exposure on self-reported heat strain symptoms among pregnant and postpartum women in South Africa

Abstract Heat exposure can harm pregnant and postpartum women, yet heat strain symptoms in this population remain underexplored. This study implemented a novel mobile application and assessed the environmental context of five self-reported heat strain symptoms: skin rashes, sleep...

Substance Use during Pregnancy: A Retrospective Multicenter Clinical Report from Four Italian Centers

Background: Rising substance use during pregnancy is a major global health concern associated with adverse maternal and neonatal outcomes. Despite growing international literature, Italian real-world multicenter data remain limited. Methods: We conducted a retrospective descripti...

Development and Internal Validation of a Clinical Risk Score for Hypovitaminosis D in Italian Adults Aged ≥50 Years Attending Osteoporosis and Metabolic Bone Disease Centers

Background/Objectives: Hypovitaminosis-D is a highly prevalent condition worldwide, associated with adverse skeletal and extra-skeletal outcomes. Increasing demand for serum 25-hydroxyvitamin D (25(OH)D) testing points toward the need for simple tools to identify individuals at r...

Child and adolescent psychiatry and mental health research "MI VEDETE?" project: a value-based and participatory approach to adolescent mental health in Italian schools

The “MI VEDETE?” (“Do You See Me?”) project explores adolescent mental health, identifying emotional distress and preventing mental health disorders through co-designing the solutions with upper secondary school students, families, and educators within the school environment. The...

Modelling air pollution concentrations via spatio-temporal Bayesian quantile regression

Abstract Exposure to high air pollution levels, especially in urban contexts, is a major risk factor for human health. Most models in literature, however, focus on the bulk of the distribution, and only few address its extremes, such as the right tail. In this work, we apply a Ba...