Azienda Ospedaliero-Universitaria di Modena

Impact of Menopause and Menopausal Hormone Therapy on Liver–Kidney–Metabolic Health

Menopause is associated with unfavorable metabolic changes that may contribute to the development of metabolic dysfunction-associated steatotic liver disease (MASLD), chronic kidney disease (CKD), and increased cardiometabolic risk. Within the evolving cardiovascular-kidney-metab...

Real‐world outcomes of venetoclax plus hypomethylating agents in unfit acute myeloid leukaemia: Results of the GIMEMA AML2320 trial

Summary Venetoclax (VEN) plus hypomethylating agents (HMAs) represents the standard of care for newly diagnosed acute myeloid leukaemia (AML) patients unfit for intensive chemotherapy, but prospective real‐world observational data outside randomized clinical trials remain limited...

From regulatory approval to clinical practice: real-world eligibility for anti-amyloid monoclonal antibodies in an Italian dementia-care network

Background: European approval of lecanemab and donanemab has shifted anti-amyloid monoclonal antibodies from trial evidence to health-system implementation. In Italy, reimbursement decisions are pending, and real-world estimates of treatment-ready eligibility under Italian approp...

Diagnostic accuracy of artificial intelligence for fracture detection on radiography and computed tomography: A systematic review and meta-analysis of externally validated clinician-comparative studies

Objectives: This systematic review evaluated externally validated, clinician-comparative studies of artificial intelligence (AI)-based fracture detection on conventional radiography and computed tomography (CT) and summarized diagnostic performance by imaging modality. Material a...