Azienda Ospedaliera Universitaria Università degli Studi della Campania Luigi Vanvitelli

High-fat diet promotes T cell–mediated synaptic dysfunction in multiple sclerosis

Early glutamatergic synaptopathy contributes to disease progression in multiple sclerosis (MS), leading to excitotoxic synaptic damage. Although high-fat diet (HFD)–associated peripheral inflammation has been linked to central nervous system dysfunction, how metabolic and immune...

Giovanni Antonio Scopoli's De Hydrargyro Idriensi Tentamina (1761): Mercury Mining, Mercurialism, and Preventive Reasoning in Eighteenth‐Century Occupational Medicine

Giovanni Antonio Scopoli (1723-1788), a physician-naturalist of the Enlightenment, is primarily remembered for his contributions to botany and entomology. Less attention has been paid to his medical work De hydrargyro Idriensi Tentamina physico-chymico-medica (1761), written duri...

Ethics in entrepreneurship: the lesson taught in the Leucian Code promulgated by King Ferdinand IV of Bourbon in 1789

Purpose Scholars continually propose new models, conceptual frameworks and approaches to advance research on ethics in entrepreneurship. As a result, a heterogeneous set of proposals has emerged that, rather than fostering research on this topic, risks delaying or hindering it. S...