Azienda Ospedaliera San Giovanni Addolorata

Focused Ultrasound-Mediated Blood–Brain Barrier Opening for Enhanced Drug Delivery in Diffuse Gliomas: A Systematic Review

Background/Objectives: The blood–brain barrier (BBB) severely limits the intratumoral delivery of systemically administered therapeutics in diffuse gliomas, including glioblastoma (GBM), contributing to the persistently poor prognosis of these tumors. Focused ultrasound (FUS) com...

Balanced versus hybrid phacoemulsification tips in grade 3 nuclear cataracts: a prospective randomized clinical study

To compare intraoperative efficiency and early postoperative corneal endothelial parameters between a balanced metal phacoemulsification tip and a hybrid polymer-coated tip. In this prospective randomized clinical study, patients with grade 3 nuclear cataract were assigned to pha...

Primary Pap Smear Cytological Diagnosis of ASC-US: HR-HPV Genotyping and Follow-Up of HPV-Positive Patients

ASC-US refers to cytological abnormalities suggestive of squamous intraepithelial lesions (SILs) that are qualitatively or quantitatively insufficient for a definitive diagnosis. In addition to HPV infection, which is the etiological agent of preneoplastic and neoplastic cervical...