Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo

Microplastics and the Kidney: A Narrative Review of Human Evidence, Molecular Mechanisms of Cell Injury, and Future Directions

Microplastics (MPs) are widespread environmental contaminants, but their potential effects on kidney health remain poorly defined. As an organ continuously exposed to circulating particles and involved in their urinary elimination, the kidney may represent both a target of MP tox...

Cardiovascular Risk Assessment in Childhood: Focus on Family History and Lifestyle Habits in the Real-World, Cross-Sectional, Community-Based RISCAPED Study

Background and Objectives: Pediatric cardiovascular risk factors tend to track into adulthood, accelerating the atherosclerotic process. This study aimed to assess the prevalence of cardiometabolic risk factors, integrating anthropometric parameters, central adiposity indices, ea...

Botulinum Toxin for Temporomandibular Disorder: Current Evidence, Clinical Applications, and Future Perspectives

Temporomandibular disorders (TMDs) are heterogeneous musculoskeletal conditions frequently characterized by pain, impaired mandibular function, and reduced quality of life. Botulinum neurotoxin type A (BoNT-A) has emerged as a potential therapeutic option, particularly for persis...

Postpandemic Trends in Pediatric Respiratory Virus Hospitalizations: A Multicenter Study, 2019–2025

ABSTRACT Background The COVID‐19 pandemic profoundly altered the circulation of respiratory viruses in children, changing the epidemiology of acute lower respiratory tract infections. In the postpandemic period, respiratory pathogens showed marked temporal variability. The 2024–2...

Beyond Device Safety: Organisational Burden and Quality of Life in Oncology Outpatients with PICCs. A Descriptive Exploratory Study

Background and Objectives: Cancer care is increasingly delivered through outpatient pathways, thereby progressively transferring part of the organisational and practical workload of care to patients and informal caregivers. Although peripherally inserted central catheters (PICCs)...

Incidence and Risk Factors of Unplanned Emergency Department Transfers From Italian Nursing Homes: A Prospective Multicentre Cohort Study

ABSTRACT Aim To estimate the incidence of unplanned transfers to the emergency department among nursing home residents and to identify resident and organizational factors associated with transfer risk. Design A 12‐month prospective multicentre dynamic cohort study. Methods The st...

Real‐world outcomes of venetoclax plus hypomethylating agents in unfit acute myeloid leukaemia: Results of the GIMEMA AML2320 trial

Summary Venetoclax (VEN) plus hypomethylating agents (HMAs) represents the standard of care for newly diagnosed acute myeloid leukaemia (AML) patients unfit for intensive chemotherapy, but prospective real‐world observational data outside randomized clinical trials remain limited...

Percutaneous Axillary Venting During Venoarterial Extracorporeal Membrane Oxygenation: A Cost-Effective Bridge Strategy for Cardiac Arrest

Left ventricular (LV) distension is a life-threatening complication of venoarterial extracorporeal membrane oxygenation (VA-ECMO), requiring prompt venting in the setting of uncertain neurological prognosis. Current strategies, microaxial devices and surgical venting, are costly...