Australian Research Council

Protein Self-Assembly as a Design Principle for Enzyme Immobilisation in Biocatalysis

Enzyme immobilisation is essential for translating biocatalytic processes from the laboratory to industrial applications by improving enzyme stability, recovery, and reuse. It underpins sustainable processes in pharmaceuticals, biofuels, and food production, but conventional immo...

Self‐Powered, Ultra‐Sensitive InGaAs/ITO Nanowire Radial Junction Infrared Photodiode for Low Flux Imaging at Room Temperature

ABSTRACT Shortwave infrared (SWIR) photodetection and imaging are of increasing importance for many emerging applications, such as optical and quantum communications, night vision, biomedical imaging and sensing. While planar InGaAs and Ge‐based SWIR photodetectors are the curren...

A fast radio burst at redshift 2, three billion years after the Big Bang

Fast radio bursts (FRBs) are millisecond-duration radio transients from extragalactic sources. Their frequency and polarization properties are affected by plasma and magnetic fields along the line of sight to Earth. We report radio observations of FRB 20240304B and near-infrared...

Correlates of Multidimensional Sleep Profiles of Young Children

ABSTRACT Despite sleep's multidimensional nature, previous research has focused on correlates of individual sleep dimensions. This study aimed to characterise young children's nighttime sleep profiles based on duration, timing, latency and quality, and to examine potential correl...

A conserved tyrosine motif encodes a structural vulnerability controlling stability and activity across J-domain proteins

J-domain proteins (JDPs) direct Hsp70 functions through a conserved J-domain that engages and activates Hsp70. JDPs support proteostasis and are linked to development and disease, yet how they are regulated remains unclear. Here, we identify a conserved tyrosine motif outside the...

Effect of a community-based sleep extension intervention on young adults’ sleep and risky driving propensity: a randomised controlled trial

Background Insufficient sleep is a key risk factor for road vehicle crashes in young adults. This trial evaluated the effectiveness of a sleep extension intervention on reducing on-road risky driving in young adult drivers who self-identified as sleepy. Methods Australian drivers...

Surface Functional Group Engineering of MXenes: Mechanisms, Tailoring Strategies, and Performance‐Oriented Applications

MXenes, as an emerging 2D material, hold considerable energy storage potential. However, the intrinsic stochastic distribution and thermodynamic metastability of their surface functional groups impair key electrochemical properties, compromising their cyclability and rate capabil...

Machine learning-based temperature mapping in Sydney: Accuracy, transferability, and scalability

Urban heat is a growing concern for public health, energy demand, and urban liveability. High-resolution air temperature (T a ) data are needed for developing effective, localised adaptation strategies, but obtaining such data at the city scale remains a challenge as weather stat...

Eating disorders and disordered eating in the forensic and correctional system: a scoping review

Eating disorders (EDs) and disordered eating (DE) occur at disproportionately high rates among populations with elevated psychosocial risk factors, such as Indigenous people, LGBTQIA individuals and those with trauma or mental illness, all of whom are overrepresented in forensic...

Environmental conditions shape the movement patterns of a marine ambush predator on homogeneous soft sediment habitat

Abstract Background Quantifying the patterns and drivers of animal movement is critical to the effective conservation and management of species across all ecosystems. Despite their importance for global commercial and recreational fisheries, the movement patterns of marine soft s...

Disrupted cerebellar networks in uncontrolled focal to bilateral tonic–clonic seizures

Abstract Objective Focal to bilateral tonic–clonic seizures (FBTC) are associated with significant morbidity and an elevated risk of sudden unexpected death in epilepsy (SUDEP). The cerebellum has been implicated in modulating the frequency and severity of tonic–clonic seizures....

Dual d– p hybridization in Ternary PtGaGe Enables Concurrent Activity and Stability Enhancement for Alkaline Oxygen Reduction

ABSTRACT The activity–stability trade‐off in oxygen reduction reactions (ORR) fundamentally limits the practical development of Zinc–air batteries (ZABs) and fuel cells. Here, we address this long‐standing challenge through spatial electronic engineering that enables dual d–p orb...

Skull morphology of the extinct Tasmanian tiger suggests unique biting style

Abstract The recently extinct thylacine (Tasmanian tiger) was the largest modern marsupial predator. It is considered a classic example of evolutionary convergence due to striking similarities with placental canids (e.g., foxes and wolves), particularly in the skull, despite ~160...

Navigating regulatory fragmentation in the convergence of synthetic biology, artificial intelligence, and automation

The convergence of synthetic biology, artificial intelligence (AI), and automation (SynBioxAI) creates research activities that simultaneously engage biosecurity, AI governance, export control, and data sovereignty frameworks – none of which are designed for convergent science. W...

X-ray computed tomography for geometallurgical ore texture analysis: Implications for comminution response

This study provides an automated workflow for downhole ore texture analysis from drill-core X-ray computed tomography (XCT) and evaluates its relevance to comminution responses. A total of 186 m of intact drill core from four drill holes in the Kalkaroo copper-gold deposit in Sou...

Advances in understanding of plasmid biology through the application of transposon insertion sequencing

Plasmids are extra-chromosomal DNA molecules capable of autonomous replication, stable inheritance in a bacterial population, and horizontal transfer to other bacteria. Plasmids can harbour auxiliary genetic material that contributes to host bacterial fitness, the most prominent...