Australian and New Zealand Urogenital and Prostate Cancer Trials Group

Management and outcomes of renal colic in pregnancy: A 10-year Australian tertiary centre experience

Objective: To describe the presentation, management and maternal-foetal outcomes of pregnant patients with symptomatic upper tract obstruction. Patients and methods: A retrospective cohort study was performed of pregnant patients managed for renal colic or symptomatic hydronephro...

Insulin‐Like Growth Factor Axis and Survival in Metastatic Hormone‐Sensitive Prostate Cancer: Post‐Hoc Analysis From the ENZAMET Phase 3 Trial

ABSTRACT Background A higher ratio of IGF‐1:IGF binding protein 1 (IGFBP1) was associated with improved prognosis in the CHAARTED trial of docetaxel in participants with metastatic hormone‐sensitive prostate cancer (mHSPC). The ENZAMET trial demonstrated the survival benefit of a...

Pembrolizumab and Denosumab in Clear-Cell Renal-Cell Carcinoma.

BACKGROUND: Anti-PD1 immune checkpoint inhibitors (ICI) are effective in clear-cell renal-cell carcinoma (ccRCC). Preliminary data suggest inhibition of Receptor Activator of Nuclear Factor-κB Ligand (RANKL) signaling may potentiate ICI efficacy. We evaluated the activity and saf...