Augusta University

Effects of organic solvents on the depth‐of‐cure determination of conventional and bulk‐fill resin composites

This study investigated the influence of organic solvents on the depth of cure (DOC) of resin composites. Two conventional (Filtek Universal [FU] and Beautifil II [BE]) and two bulk-fill (Filtek One Bulk Fill [FO] and Beautifil-Bulk [BB]) composites were evaluated. Cylindrical sp...

DUSP4 promotes anti-tumor CD8+ T cell function and boosts CAR-T cell efficacy in mouse colorectal cancer

The activation and function of CD8+ T cells, which are central for anti-tumor immunity, are tightly regulated by extracellular and intracellular signaling pathways. Dual-specificity phosphatases (DUSP), including DUSP4, dephosphorylate serine/threonine and tyrosine residues of pr...