Augenstern

SPEF1 mediates assembly of central pair microtubule complexes in cilia of Tetrahymena

SPEF1 is a conserved calponin-homology domain protein that decorates the seam of central pair microtubules in the distal segment of motile cilia. Here, we show that in the ciliate Tetrahymena, loss of SPEF1 disrupts the central pair throughout the middle segment, which comprises...

Widefield optical coherence tomography angiography of fellow eyes in patients with Coats Disease

PURPOSE: Recent advances in retinal imaging have revealed vasculostructural alterations in fellow eyes of patients with Coats disease, thereby challenging the traditional concept of Coats disease as a strictly unilateral disorder. To further explore the phenotype of this retinal...