Atrium Health Wake Forest Baptist

Differential Susceptibility to Heavy-Metal–Induced Injury in a Human Testis Tissue Equivalent (hTTE): Implications for Oxidative Stress

Oxidative stress driven by environmental and occupational exposure to heavy metals is increasingly recognized as a central, modifiable contributor to male infertility. Yet, the lack of physiologically relevant human models has limited mechanistic insight. We have previously descr...

Indigenous Strengths, Community Care, and Cancer Disparities: Insights from Talking Circles with American Indian Tribes in North Carolina

Abstract Background: American Indian communities experience disproportionally higher cancer incidence and mortality rates compared to other populations in North Carolina (NC). As part of the SAICEP (Southeastern American Indian Cancer health Equity Partnership) initiative, talkin...

Implementing a Remote Blood Pressure Monitoring Program at Rural Resident Primary Care Clinic

INTRODUCTION: We evaluated feasibility of implementing remote blood pressure (BP) monitoring (RBPM) program in rural resident primary care clinic. METHODS: This is Internal Medicine resident physicians-led single arm RBPM study among Medicare populations with hypertension in rura...

Approach to pediatric patients with elbow injuries in the emergency department.

Pediatric elbow injuries are a common complaint presenting to emergency departments. The unique anatomy and skeletal immaturity in children can make the elbow particularly difficult to evaluate and manage. Additionally, many healthcare institutions have limited or no access to pe...

Randomized phase II trial of liposomal cytarabine and daunorubicin with or without pomalidomide in newly diagnosed acute myeloid leukemia myelodysplasia-related

Not available.

Rotator Cuff Tears Part II: Subscapularis Repair, Augmentation, and Tendon Transfer—An International Expert Consensus Statement

PURPOSE: To establish updated international consensus statements on subscapularis repair, graft/patch augmentation and superior capsular reconstruction, and tendon transfers for rotator cuff tears, reflecting new evidence, evolving techniques, and ongoing areas of controversy. ME...

Leg Muscle Assessment by HR-pQCT and DXA: Associations Between Imaging Measures and Muscle Function in Adults with Obesity – A Pilot Study

Abstract Dual energy X-ray absorptiometry (DXA) and high-resolution peripheral quantitative computed tomography (HR-pQCT) are used for bone assessment but also image adjacent soft tissue. This pilot study examined association between HR-pQCT-measured leg muscle cross-sectional ar...

Patterns of head and neck pain and obstructive sleep apnea in women with macromastia: A cross‐sectional analysis

Abstract Objectives/Background Symptomatic macromastia, or breast hypertrophy, is associated with musculoskeletal and neurological symptoms, including headache and neck pain. Though insurers list headache as an indication for breast reduction surgery, its relationship to specific...

Rotator Cuff Tears Part I: Diagnosis, Nonoperative Management, and Repair of Posterosuperior Tears—An International Expert Consensus Statement

PURPOSE: To establish updated international consensus statements on the diagnosis, nonoperative management, and repair of posterosuperior rotator cuff tears, reflecting new evidence, evolving techniques, and ongoing areas of controversy. METHODS: A consensus process on the treatm...

Early Satiety in Cancer ‒ the Symptom Experience: Exploratory Cross-Sectional Cohort Study

Background Early satiety (ES) is a common symptom in several conditions, including cancer. Despite presenting at all cancer stages, little is known about how patients describe ES. This study aimed to explore the lived experience of those with ES. Methods A cross-sectional study w...

Evaluating the Implementation Fidelity of the REJOIN (Using Exercise to Relieve Joint Pain and Improve Aromatase Inhibitor Adherence in Older Breast Cancer Survivors) Pilot Trial

Implementation fidelity (IF), the extent to which interventions are delivered as intended, is essential for assessing program integrity and informing future dissemination/scalability. The REJOIN pilot trial adapted Fit & Strong! ( F&S! ) to deliver an education/exercise intervent...

Cardiolipin deficiency disrupts electron transport chain and drives steatohepatitis

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a progressive disorder marked by lipid accumulation, leading to metabolic dysfunction-associated steatohepatitis (MASH). A key feature of the transition to MASH involves oxidative stress resulting from defects in...

Superlarge-Bore Versus Large-Bore Aspiration Catheters in Mechanical Thrombectomy: A Multicenter Propensity-Matched Analysis

BACKGROUND AND OBJECTIVES: Aspiration catheters are an integral component of mechanical thrombectomy for acute ischemic stroke (AIS). Following early series demonstrating increasing procedural efficiency and improved outcomes with use of large-bore (LB) aspiration catheters, ther...

Metabolic Dysfunction–Associated Steatotic Liver Disease: An Underrated and Emerging Cardiovascular Risk Factor

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease worldwide and is increasingly recognized as a major contributor to cardiovascular morbidity and mortality. Beyond liver involvement, MASLD represents a systemic metabolic...

The hematology workforce in the United States: past, present, and strategies for the future

From 2017-2021, the American Society of Hematology (ASH) completed the largest study ever conducted of the hematology workforce in the United States (US). The study highlighted a deficit in the classical hematology (CH) workforce: despite very high CH clinical volumes encountered...

Surgical Management of Young Women with High-Risk Breast Cancer Receiving Neoadjuvant Systemic Therapy on the I-SPY2 Trial

BACKGROUND: Mastectomy rates in women with breast cancer are higher in younger women than in older women. The impact of this more extensive surgery on overall survival (OS) and locoregional recurrence in younger women is unknown, especially after neoadjuvant systemic therapy (NST...