AstraZeneca (Germany)

Epithelial–mesenchymal transition in carcinoma: navigating phenotypic states to target resistance and metastasis

Epithelial–mesenchymal transition (EMT), historically described as a binary morphological change from an epithelium to a mesenchymal state, no longer adequately accounts for carcinoma cell phenotypes observed in patients. Single-cell sequencing, spatial-omics, and lineage tracing...