Association of Public Health Laboratories

Pattern Agency on Active Media (ver. 5.0)

This article follows from one sentence about the world: that the substrate is a diffusion whose fluctuations are nowhere degenerate. That single assumption turns out to carry a surprising amount. The geometry of the state space is not imposed on it but is the covariance of its ow...

Decision Analysis to Inform Screening of the Young: An Interactive Newborn Screening Model

Decision analytic models that project the outcomes of population-based newborn screening compared with clinical identification can inform newborn screening policymaking. A flexible decision analytic model that could be adapted for the many and growing number of conditions being c...

Memory B Cell Repertoire of a Repeatedly Vaccinated Individual Includes Influenza Hemagglutinin-Specific Cross-Group Binders with Affinity Beyond A(H1N1)pdm09 and A(H3N2) Seasonal Strains

Background/Objectives: Humans are primarily infected by two distinct seasonal influenza A virus (IAV) subtypes, A(H1N1)pdm09 and A(H3N2). Because IAV mutates rapidly, it continuously escapes existing protective antibodies. However, repeated exposure to these evolving strains incr...