Armauer Hansen Research Institute

A Review of National Response to Noncommunicable Diseases through a Health System Readiness Lens in Ethiopia: From Policy to Practice

Background Ethiopia faces an increasing issue with noncommunicable diseases (NCDs), such as cardiovascular diseases, diabetes, cancers, and chronic respiratory conditions. Although national policies and strategies have been developed to address this issue, their implementation is...

Thermotherapy compared with intralesional sodium stibogluconate for Leishmania aethiopica cutaneous Leishmaniasis in Ethiopia: A phase II randomized controlled trial

Cutaneous leishmaniasis (CL) is a significant public health challenge in Ethiopia with an estimated 20,000–30,000 new cases annually. Despite this high disease burden, management is constrained by limited therapeutic options and lack of local clinical trial evidence to guide rout...

Immunohistochemical profiling of the tumor microenvironment in Ethiopian breast cancer tissue: insights into pathology and subtypes

Breast cancer (BC) is the most common malignancy globally and poses a significant public health challenge in sub-Saharan Africa (SSA). To date, the clinical use of immunotherapies has improved patients’ outcomes in high-income countries, but is not feasible in most countries in S...

Prevalence of virulence-associated genes in culture-confirmed Vibrio cholerae isolates: a PCR-based study

Vibrio cholerae remains a major cause of cholera outbreaks in Ethiopia, yet information on the distribution of virulence-associated genes among circulating strains is limited. This study aimed to detect major virulence genes in culture-confirmed V. cholerae isolates recovered fro...

Tongue swab Xpert MTB/RIF Ultra for tuberculosis diagnosis in Ethiopian prisons

Tuberculosis (TB) diagnosis remains a major challenge in Ethiopian prisons, where access to diagnostics is limited. Current TB diagnostic strategies in Ethiopian prisons rely primarily on sputum-based testing. However, sputum collection is often challenging due to logistical barr...

Isolation and identification of Pseudomonas fluoeroscens and evaluation of its antimicrobial sensitivity from fish in Lake Haramaya, East Hararghe Zone, Oromia Regional State, Ethiopia

Abstract Pseudomonas fluorescens ( P. fluorescens ) is an opportunistic Gram-negative bacterium associated with disease in freshwater and marine fish, resulting in economic losses to aquaculture. This study aimed to isolate and identify P. fluorescens from wild Nile tilapia ( Ore...

Prevalence of cervical human papillomavirus infections and cytological abnormalities in asymptomatic women living with HIV in Addis Ababa, Ethiopia

Cervical cancer from persistent HPV infection is the leading cause of cancer death among Sub-Saharan African women. We here addressed the existing knowledge gap concerning the prevalence of HPV infection and cervical lesions in asymptomatic women living with HIV (WLWH) in Addis A...

Building the toolkit to address malaria resurgence and radical cure of vivax malaria in Ethiopia: a meeting report

Abstract Ethiopia has experienced a substantial resurgence in malaria in recent years, with increasing case numbers and a growing contribution of Plasmodium vivax in several regions. At the same time, new evidence supporting improved radical cure strategies, including high-dose p...